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Looking for a Laboratory
Gas Generator?
Jencons (Scientific) Ltd are a leading laboratory
equipment supplier in the UK. We offer a wide range of Gas Generators
for the Laboratory.
Our range of gas generators
includes:
- Nitrogen generators
- Clean dry air generators
- CO2-free generators
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- Hydrogen generators
- Zero air generators
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in a wide range of specifications
and prices. |
If you are looking for a domnick hunter gas generator
you will see a full range featured, either in our published 1100
page catalogue or you can find full details and buy online at
www.ecomcat.co.uk , the Jencons online catalogue.
Gas generators are required
increasingly in the laboratory for a wide range of applications
including:
- Liquid Chromatography/Mass Spectrometry (LC/MS)
- Gas Chromatography/Mass Spectrometry (GC/MS)
- Nuclear Magnetic Resonance (NMR)
- Molecular Spectroscopy (FT-IR)
- Evaporative Light Scattering Detection (ELSD)
- Gas Chromatography (GC)
- Atomic Absorption (AA)
- Inductively Coupled Plasma Spectrometry (ICP)
- Total Organic Carbon (TOC)
- Total Inorganic Carbon (TIC)
- Total Hydrocarbon Analysis (THA)
- Thermal Gravimetric Analysis (TGA)
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All of these applications
require a reliable source of high purity analytical grade gas. |
Taking LC/MS as an example-
this technique uses
high pressure liquid chromatography (HPLC) to first separate out
components of a mixture (i.e. your sample). As the name suggests
a liquid mobile phase is used which usually consists of a combination
of water and an organic solvent. The mass spectrometer is used
to then measure the mass-to-charge ratio of the ions present in
the components- producing a mass spectrum. Analysis of the mass
spectrum then ultimately leads to the identification of the compounds
in the initial mixture entered into the HPLC.
In mass spectrometry the sample must first be
ionised before it enters the analyser and the ions are separated
and then detected based on their mass to charge ratio. It is this
ionisation stage which requires the use of a high purity analytical
grade gas. One of the most commonly used methods of ionisation
in LC/MS is electrospray ionisation (ESI). A liquid, in which the
analyte(s) of interest have been dissolved, is passed through a
capillary, at atmospheric pressure, maintained at high voltage. The
liquid stream breaks up with the formation of highly charged droplets
which are desolvated as they pass through the atmospheric-pressure
region of the source towards a counter electrode. Desolvation
is assisted by a stream of a drying gas, usually nitrogen, being
continually passed into the spraying region. Analyte ions
are obtained from these droplets which then pass through two differentially
pumped regions into the source of the mass spectrometer. It can
be seen that a reliable gas supply is essential in the ionisation
step of mass spectrometry. For this reason a Nitrogen gas generator
is recommended.
LC/MS is used in a wide range of disciplines,
including:
| Proteomics - |
- Protein Identification
- Protein
Characterisation
- Quantitation & Expression
Analysis
- Protein
Biomarker Validation
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| Drug Discovery - |
- Lead Generation & Identification
- Lead Optimisation & Early AMET
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| Drug Development - |
- Drug Metabolism
- Pre-Clinical ADMET
- Clinical Trials
- Manufacturing QA/QC
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| Testing & Identification - |
- Forensics/Human Identification
- Food
- Agriculture
- Environmental
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All of these applications
require a reliable source of high purity analytical grade gas. |
Our online catalogue features the very latest
ranges of domnick hunter gas generators, browse on E-comcat under “gas” for
our latest range.
We can also source products outside the scope of either catalogue
so please contact us whatever your equipment requirements are.
| Find
out more… |
Buy
online… |
Request
a Quote… |
Full details of our most up-to-date range of gas generators
are available on E-comcat...here
You
can view a downloadable PDF of the gas generator section
in our 1100 page catalogue...here
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View
details on our most up-to-date range of gas generators
and order online on E-comcat our online catalogue …here
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We
can quote for your gas generator requirements…here
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